Lutetium-177 FAPI Therapy

Lutetium-177 DOTATATE therapy for neuroendocrine tumor

What is Lutetium FAPI Therapy?

Lutetium-177 (Lu-177) FAPI therapy is a theranostic technique emerging as a potential weapon against various cancers. It combines the capabilities of diagnosis and treatment into a single approach, offering a targeted and personalized strategy.

Who Might Benefit?

Lu-177 FAPI therapy is a potential option for patients with:

How it Works?

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Discover the future of healthcare at Kiran Nuclear Medicine and PET CT Center. Our pioneering theranostics approach not only diagnoses but also tailors treatment plans specific to your needs, ensuring precise and effective care. Experience the power of personalized medicine with us.
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Pioneering Theranostics

At Kiran Nuclear Medicine and PET CT Center, we're leading the way in theranostics, integrating advanced diagnostics with personalized treatment plans.

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Precision and Effectiveness

Our commitment to theranostics means that you receive precise diagnoses and targeted therapies, leading to more effective treatment outcomes. We leverage cutting-edge technology and expertise to deliver the highest standard of care.

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Personalized Medicine

We prioritize your individual health needs, providing customized treatment plans that consider your medical history, preferences, and treatment goals.

Meet Our Doctors

Dr Kiran Kumar JK

Dr Kiran Kumar JK

Founder and Director MBBS, MD(PGIMER)
Dr Manoj Devanathan

Dr Manoj Devanathan

Medical Director MBBS, MD(JIPMER)
Dr Abhiram GA

Dr Abhiram GA


Frequently asked questions

What is Lutetium-177 FAPI Therapy?

Lutetium-177 FAPI Therapy is a novel targeted radionuclide therapy used in the treatment of various solid tumors, particularly those that overexpress fibroblast activation protein (FAP). It involves the administration of a radioactive isotope, Lutetium-177, coupled with a FAP-targeting ligand. This combination allows for the selective delivery of radiation to FAP-expressing tumor cells.

How does Lutetium-177 FAPI Therapy work?

Fibroblast activation protein (FAP) is a cell surface protein that is overexpressed in the stroma of many solid tumors, including pancreatic, colorectal, and lung cancers. Lutetium-177 FAPI Therapy utilizes a ligand that specifically binds to FAP. When coupled with Lutetium-177, a beta-emitting radionuclide, this ligand delivers radiation directly to the FAP-expressing tumor cells, leading to their destruction.

Who is a candidate for Lutetium-177 FAPI Therapy?

Lutetium-177 FAPI Therapy may be considered for patients with advanced or metastatic solid tumors that express high levels of FAP. It is typically recommended for patients who have exhausted standard treatment options or who are not candidates for surgery, chemotherapy, or other therapies.

Is Lutetium-177 FAPI Therapy safe?

Lutetium-177 FAPI Therapy is generally considered safe when administered by trained healthcare professionals in specialized nuclear medicine facilities. However, like any medical treatment, there are potential side effects and risks associated with the therapy, including bone marrow suppression, kidney damage, and radiation exposure to other tissues. Patie

What should I expect during Lutetium-177 FAPI Therapy?

Before undergoing Lutetium-177 FAPI Therapy, patients may undergo imaging studies such as PET/CT scans with FAPI tracers to assess the extent of disease and FAP expression. The therapy itself involves the intravenous administration of Lutetium-177 FAPI, typically as a series of treatments spaced several weeks apart. Patients may experience side effects such as fatigue, nausea, and decreased blood cell counts, which are usually temporary and manageable

What are the expected outcomes of Lutetium-177 FAPI Therapy?

Lutetium-177 FAPI Therapy is a relatively new treatment approach, and clinical data regarding its efficacy are still emerging. Preliminary studies have shown promising results, with some patients experiencing tumor shrinkage, symptom relief, and improved quality of life. However, more research is needed to fully understand the potential benefits and limitations of this therapy. Patients interested in Lutetium-177 FAPI Therapy should discuss this treatment option with their healthcare provider to determine its suitability for their individual circumstances.

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