PSMA PET Scan in Bangalore
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PSMA PET Scan:
PSMA PET Scan- What it Can Detect?
PSMA PET Scans have shown potential in identifying prostate cancer accurately, even in cases when standard imaging techniques such as CT scans and bone scans are not sensitive enough to detect smaller lesions or metastases.
- PSMA PET/CT or PET/MRI scans can aid in tumour staging, checking the extent of spread, identifying lymph node involvement, and finding metastases that are even distant.
- PSMA-targeted treatments for prostate cancer, such as PSMA-targeted radionuclide therapy (PRRT), have additionally been developed. These treatments provide a radioactive payload directly to cancer cells that express PSMA while preserving the other healthy tissues.
- PSMA scans and treatments continue to be researched and modified, while ongoing clinical trials are investigating their efficacy in different stages and forms of prostate cancer.
Working Principle of PSMA PET Scan
- The radiotracer is injected into the patient, where it circulates through the circulation and selectively binds to PSMA receptors on prostate cancerous cells and any metastases throughout the body.
- The radiotracer decay is then detected via positron emission tomography (PET) imaging, which detects the released positrons.
- PET scan data is coupled with computed tomography (CT) or magnetic resonance imaging (MRI) data to produce fused pictures that include anatomical and functional data.
- The PSMA PET/CT / PSMA PET/MRI images that result facilitate the visualisation and positioning of PSMA-expressing prostate cancer cells, assisting in the identification, staging, and monitoring of prostate cancer.
- PSMA scans are very beneficial for diagnosing recurring or metastatic prostate cancer, as well as finding tiny tumours that conventional imaging might fail to identify.

Early Examination: Benefits Of Doing It
- PSMA scans offer high sensitivity, allowing for the diagnosis of prostate cancer at an early stage when it is most curable and treatable.
- PSMA scans can appropriately stage prostate cancer, revealing vital information regarding the tumour's size and spread inside the prostate and adjacent tissues.
- PSMA scans can precisely pinpoint PSMA-expressing tumours, allowing medical professionals to target and undertake biopsies for concerning regions, with greater efficiency.
- Early detection using PSMA scans allows for the selection of more appropriate and personalised treatment choices depending on the specific attributes and characteristics of the prostate cancer.
- Early diagnosis along with proper staging using PSMA scans may result in better treatment results and a better long-term prognosis for prostate cancer patients.
PSMA PET Scan Protocols: Steps You Must Follow Before The Examination
- Before the PSMA scan, blood tests may be conducted to assess the patient's kidney function and other relevant parameters to ensure they are suitable for the procedure.
- In some cases, you may be asked to fast for a specific period (typically about 6 hours) before the scan.
- Patients are encouraged to drink plenty of water before the scan to help flush out excess radioactivity from the body.
- Based on the specific radiotracer used and your medical condition, you may be asked to discontinue certain medications temporarily before the scan.
- Please keep us informed regarding your medical conditions, especially if you are diabetic, pregnant or breastfeeding.
- The patient will be administered the radiotracer intravenously. The radiotracer contains a small amount of radioactive material that will bind to PSMA-expressing cells.

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Yes, PSMA scans have a high sensitivity, allowing them to detect tiny and early-stage prostate cancer malignancies before they are detectable on other imaging tests.
Patients are usually urged to keep hydrated, fast if required, and to inform their healthcare professional about any prescription medications, specific medical conditions or allergies.
Yes, as mentioned, PSMA scans are very sensitive in detection. And the same holds good for recurring prostate cancer, even at low PSA levels, they are useful for monitoring treatment efficacy and detecting cancer recurrence.